Miss Happy stars Pancake Khemanit as a happy-go-lucky woman named Happy, who often annoys her best friend Golfie (Ben Chalatit). Unfortunately, Happy is diagnosed with having an irregular heartbeat that will likely cause her death within a month. In an effort to survive, Happy looks up information and finds a YouTube video made by Tul, played by Jitpanu Klomkaew (Ball). Tul's video claims that Happy can stay alive if she dances in the way shown in the video.
The plot of the show revolves around Abby, who, upon discovering her high school crush’s preferred coital position, seeks to familiarize herself with it with the assistance of a local stripper. However, as Abby grapples with the idea of advancing their re